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Protect against AI‑scaled attacks across email and beyond

Secure trusted interactions across multiple channels and stages with a single strategic partner
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Enable humans and AI agents to trust agentic workspace collaboration.

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As organizations enter the agentic era, attack surface further expands

Threat actors are using AI to take full advantage of how humans work—exploiting trust across employees, business partners, and AI systems themselves.

Modern attacks are AI-driven, multichannel, and multistage, linking email, collaboration and messaging tools, social media, cloud apps, and now AI agents to target people at scale. New AI-specific exploits, including weaponized messages and malicious prompts, further increase risk.

Fragmented security slows response times, siloes teams, and increases cost, leaving critical gaps across collaboration channels—exactly where attackers are accelerating.

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of users who take risky behavior are aware of the potential dangers
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the average cost of a data breach, underscoring the financial impact of inadequate and fragmented security measures
$ 0 M
increase in URL threats delivered through smishing attacks
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Collaboration Security Prime — secure trusted interactions in the agentic workspace

Proofpoint Collaboration Security Prime is our premium solution for protecting trusted interactions and stopping AI-scaled attacks across multiple channels and stages. Built on our industry-leading email security, Prime extends protection beyond email to messaging and collaboration tools, cloud applications, and the supply chain—all through a single, integrated platform.

Prime embeds human resilience directly into the platform, turning real attacks into instant training and simulations. By correlating security events across multiple control points throughout an attack campaign, it accelerates threat response, streamlines operations, and unifies siloed teams.

of the Fortune 100 trust Proofpoint
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the average cost of a data breach, underscoring the financial impact of inadequate and fragmented security measures
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of the Fortune 1000 protect their trusted domains using Proofpoint, more than the next 5 vendors combined
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Key features and capabilities include:

Multichannel defense with Nexus AI

Protects organizations’ employees across email, messaging, browsers, collaboration tools, social media platforms, cloud apps and file-sharing services. Nexus AI applies consistent threat detection across all digital channels to eliminate blind spots, ensuring full-surface protection.

Multistage attack protection

Identifies and remediates account takeovers, lateral movement and supply chain attacks through a unified detection and response workflow. Provides full visibility and ability to investigate and act faster.

Human risk-based guidance and insights

Identifies at-risk employees and obtain AI-driven risk insights based on user behavior and threat activity. Provides employees real-time, risk-based guidance and targeted education tailored to their attack exposure, behavior and roles. Enables security teams to apply adaptive security controls and coach at-risk employees.

Impersonation protection

Protects trusted domains from various impersonation tactics, such as domain spoofing and malicious lookalikes, using an integrated system that combines email authentication, dynamic discovery of malicious lookalike domains, and takedown services.

Experience the benefits of Collaboration Security Prime

on average in reduced risk exposure
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Achieve completeness of risk reduction

Unlike others that only detect a limited range of threats, Collaboration Security Prime delivers comprehensive protection, preventing the widest array of threats with unrivaled detection accuracy. It blocks threats delivered through various channels, strengthens user resilience and defends against both compromised user and supplier accounts. And it safeguards your trusted business communications while providing deep insights into human risk—ensuring complete security like no one else.
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improvement in workforce efficiency
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Simplify operations for maximum efficiency

Collaboration Security Prime streamlines security operations by minimizing triage-worthy alerts with industry-leading 99.99% detection accuracy. It reduces labor costs and mitigates the impact of threats through automated workflows and threat response capabilities—improving workforce efficiencies by as much as 75%.
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saved by optimizing IT
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Achieve more with less through consolidation

With preconfigured integrations across the Proofpoint ecosystem, Proofpoint Collaboration Security eliminates the complexity and overhead of managing fragmented point solutions. You can maximize licensing benefits and unlock access to advanced capabilities at a significantly better value by consolidating vendors and choosing Proofpoint as your single strategic partner.
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See the latest Proofpoint Collaboration Security Prime innovations

SSO Password Guard

SSO Password Guard blocks re-use of corporate passwords on any unsanctioned website or application, reducing risk of credential loss and account compromise.

Threat Interaction Map

Threat Interaction Map visualizes user interactions with threats across multiple channels and stages, saving SOC analysts valuable time by showing them where to focus their investigation.

AI-Powered ThreatFlip

ThreatFlip turns real-world phishing attacks into safe simulations, using AI to scrub malicious elements and PII and producing ready-to-use templates in ZenGuide, all with a single click.

Detection of AI Exploits Over Email

Blocks malicious emails with hidden AI prompts designed to exploit assistants like Microsoft Copilot or Google Duet AI before they ever reach inboxes.

Proofpoint is a complete solution that gives us full visibility into what’s going on in the communication stack, the people stack and the behavioral stack.

— The Ariston Group
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Proofpoint remains the ideal partner to help us meet the challenges of cybersecurity in an increasingly complex landscape.

— Saipem
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We only need to log into Proofpoint platform on a weekly basis because we can count on it to do its job.

— Linkforce
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Learn how Collaboration Security Prime reduces the most risks

Prime Threat Protection

Learn the key capabilities that you need to build a strong defense against all human-centric threats—both email-based and beyond.

Transforming Data Loss Prevention

This short demo showcases a real-world scenario where Proofpoint Prime stops a multichannel, multistage attack.

Accelerate your data security maturity

Learn the key tactics that cybercriminals use to compromise accounts and get a rundown of why these attacks can be challenging to stop.

Prime Threat Protection: Stop All Human-Centric Threats

Learn how Proofpoint defends against threats across email, cloud apps, collaboration and messaging tools, and more.

Stop Hijacked Business Communications: Use Case

Learn the key tactics that fraudsters use to hijack business communications.

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Learn how our integrated platform helps you:
  • Stop cyberattacks
  • Prevent data loss
  • Reduce human risk across your environment
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